首席專家

張東玲，女，博士，副教授，博士生導(dǎo)師，福建省C類人才，福建省科技特派員，兼企業(yè)技術(shù)顧問。

Emai: [email protected]

QQ: 342312933

二、研究方向

1. 魚類遺傳育種：利用多種組學(xué)方法對魚類多種性狀進(jìn)行良種選育。

2. 魚類基因組學(xué)：組裝魚類基因組，挖掘功能基因。

3. 益生菌：利用多種方法構(gòu)建或分離益生菌并應(yīng)用到生產(chǎn)。

三、近五年主持的課題

1. 國家自然科學(xué)基金面上項(xiàng)目，32172964，大黃魚抗?fàn)€身病性狀的遺傳解析，2022.01-2025.12，資助金額：75.4萬元，在研，主持。

2. 福建省種業(yè)創(chuàng)新與產(chǎn)業(yè)化工程項(xiàng)目，斑鱖和黑脊倒刺鲃種業(yè)創(chuàng)新與產(chǎn)業(yè)化開發(fā)，2022.08-2025.08，資助金額：90萬，在研，主持。

3. 福建省自然科學(xué)基金重點(diǎn)項(xiàng)目，2022J02042, 大黃魚抗盾纖毛蟲病性狀的遺傳基礎(chǔ)解析，2022.08-2025.02，資助金額：20萬，在研，主持。

4. 廈門市科技局-產(chǎn)學(xué)研后補(bǔ)助項(xiàng)目，2024CXY0320，海洋生物活性肽抗多種副溶血弧菌活性研究與開發(fā)，2024.10-2027.10，資助金額：16萬，在研，主持.

5. 企業(yè)聯(lián)合橫向，生產(chǎn)尾水處理益生菌的研發(fā)和應(yīng)用，2024.04-2027.04，資助金額：50萬，在研，主持。

6. 企業(yè)聯(lián)合橫向，大蒜E素（乙蒜素）在自然海區(qū)抗大黃魚內(nèi)臟白點(diǎn)病和盾纖毛蟲病的應(yīng)用技術(shù)研究，2024.06-2026.12，資助金額：21萬，在研，主持。

7. 企業(yè)聯(lián)合橫向，海洋生物活性肽抗多種副溶血弧菌活性研究與開發(fā)，2023.08-2028.08，資助金額：50萬，在研，主持。

8. 國家海洋水產(chǎn)種質(zhì)資源庫建設(shè)，每年資助，2019.01-至今，資助金額：5萬，在研，主持。

9. 企業(yè)聯(lián)合橫向，大蒜E素（乙蒜素）對大黃魚內(nèi)臟白點(diǎn)病防治效果研究，資助金額：5萬，2023.07-2025.03，在研，主持。

10. 福建省自然科學(xué)基金面上項(xiàng)目，2019J01692，適應(yīng)無魚粉魚油飼料大黃魚分子標(biāo)記輔助選育的基礎(chǔ)研究，2019.05-2022.06，資助金額：10萬，結(jié)題，主持。

四、代表論著

1. Yan Chunmei, Chen meiling, Jin Jian, Liu Xiande, Wang Zhiyong, Luo Yongju, Zhang Dongling(通訊作者）*. Bacillus subtilis 2118 exhibits bactericidal activity due to an inserted fish cDNA library. Aquaculture, 2024, 593:741300.

2. Tang Xin, Xiao Zhiqun,Chen meiling, Zhu Xingcheng,Wang Zhiyong, Zhang Dongling(通訊作者）*. A prototype galectin-1 (also known as galecin-2) from large yellow croaker (Larimichthys crocea): Molecular and function study. Fish & Shellfish Immunology, 2024,145:109314.

3. Chen meiling, Xiao Zhiqun, Yan Chunmei, Tang Xin, Ming Fang, Wang Zhiyong, Zhang Dongling(通訊作者）*. Centrosomal protein of 192 kDa (Cep192) fragment possesses bactericidal and parasiticidal activities in Larimichthys crocea. International Journal of Biological Macromolecules, 2024, 254:127744.

4. Chen meiling, Lin Nengfeng, Liu Xiande, Tang Xin, Wang Zhiyong, Zhang Dongling(通訊作者）*. A novel antimicrobial peptide screened by a Bacillus subtilis expression system, derived from Larimichthys crocea Ferritin H, exerting bactericidal and parasiticidal activities. Frontiers in immunology, 2023, 1168517.

5. Tang Xin, Zhu Xingcheng, Liu Xiande, Wang Zhiyong, Zhang Dongling(通訊作者）*. A unique C-type lectin, Ladderlectin, from large yellow croaker (Larimichthys crocea) is involved in bacterial cell membrane damage. Fish & Shellfish Immunology, 2023, 136:108744.

6. Li Zeyu, Fang Ming, Tang Xin, Zhang Dongling(通訊作者）*, Wang Zhiyong*. Disentangling genetic variation for endurance and resistance to visceral white-nodules disease in large yellow croaker (Larimichthys crocea) using genome information. Aquaculture, 2023, 564:739045.

7. Tang Xin, Liu Xiande, Wang Zhiyong, Chen meiling, Zhang Dongling(通訊作者）*. Molecular Characterization, Expression, and Regulatory Signal Pathway Analysis of Inflammasome Component Apoptosis-Associated Speck-like Protein Containing a CARD Domain (ASC) in Large Yellow Croaker (Larimichthys crocea). International Journal of Molecular Sciences, 2023, 24:2175.  

8. Tang Xin, Wang Zhiyong, Jiang Dan, Chen Meiling, Zhang Dongling(通訊作者）*. Expression profile, subcellular localization of MARCH4 and transcriptome analysis of its potential regulatory signaling pathway in large yellow croaker (Larimichthys crocea). Fish & Shellfish Immunology, 2022, 52:273-282.

9. Zhang ZhenXi, Wang Zhiyong, Fang Ming, Ye Kun, Tang Xin, Zhang Dongling(通訊作者）*. Genome-wide association analysis on host resistance against the rotten body disease in a naturally infected population of large yellow croaker Larimichthys crocea. Aquaculture, 2022, 548:737615.

10. Zhang Dongling, Lv Chang Huan, Yu Da Hui, Wang Zhi Yong*. Characterization and functional analysis of a galectin-9 protein in large yellow croaker Larimichthys crocea. Fish & Shellfish Immunology, 2016, 52:167-178.

11. Lv Chang Huan#, Zhang Dongling#（共同第一作者）, Wang Zhi Yong*. A novel C-type lectin, Nattectin-like protein, with a wide range of bacterial agglutination activity in large yellow croaker Larimichthys crocea, Fish and Shellfish Immunology, 2016, 50:231-241.

12. Zhang Dongling, Da Hui Yu, Jian Chen, Zhi Yong Wang*. Co-expression and interaction suggest TBK1 can be regulated by Nrdp1 in response to immune stimulation in large yellow croaker Larimichthys crocea, Fish and Shellfish Immunology, 2015, 46:745- 752.

13. Zhang Dongling, Da Hui Yu, Jian Chen, Zhi Yong Wang*. Characterization and expression analysis of BCA2 gene in large yellow croaker, Larimichthys crocea. Fish and Shellfish Immunology, 2015, 46:543-549.

14. Zhang Dongling, Fang Han, Da Hui Yu, Shi Jun Xiao, Ming Yun Li, Jian Chen, Zhi Yong Wang*.Characterization of E3 ubiquitin ligase neuregulin receptor degradation protein-1 (Nrdp1) in the large yellow croaker (Larimichthys crocea) and its immune responses to Cryptocaryon irritans. Gene, 2015, 556:98-105.

15. Zhang Dongling, Yu Da Hui, Chen Jian, Wang Zhi Yong*. Co-expression of march5b and tlr7 in large yellow croaker Larimichthys crocea in response to Cryptocaryon irritans infection, Journal of Fish Biology, 2015, 87:360-70.

16. XuHao#, Zhang Dong